(R)-2-hydroxy-fatty-acid dehydrogenase explained

(R)-2-hydroxy-fatty-acid dehydrogenase
Ec Number:1.1.1.98
Cas Number:37250-32-1
Go Code:0047049

In enzymology, a (R)-2-hydroxy-fatty-acid dehydrogenase is an enzyme that catalyzes the chemical reaction

(R)-2-hydroxystearate + NAD

\rightleftharpoons

2-oxostearate + NADH + H

Thus, the two substrates of this enzyme are (R)-2-hydroxystearate and NAD, whereas its 3 products are 2-oxostearate, NADH, and H. This reaction is important in fatty acid metabolism.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD or NADP as acceptor. The systematic name of this enzyme class is (R)-2-hydroxystearate:NAD oxidoreductase. Other names in common use include D-2-hydroxy fatty acid dehydrogenase, and 2-hydroxy fatty acid oxidase.

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