(Fructose-bisphosphate aldolase)-lysine N-methyltransferase explained

(Fructose-bisphosphate aldolase)-lysine N-methyltransferase
Ec Number:	2.1.1.259

[Fructose-bisphosphate aldolase]-lysine N-methyltransferase ^{[1] [2]} is an enzyme that catalyses the following chemical reaction:

The enzyme methylates a conserved lysine in the C-terminal part of higher plant fructose-bisphosphate aldolase (EC 4.1.2.13).

Nomenclature

The systematic name of the enzyme is:

• S-adenosyl-L-methionine:(fructose-bisphosphate aldolase)-lysine N⁶-methyltransferase

Other names are:

• rubisco methyltransferase
• ribulose-bisphosphate-carboxylase/oxygenase N-methyltransferase
• ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit epsilonN-methyltransferase
• S-adenosyl-L-methionine:[3-phospho-D-glycerate-carboxy-lyase (dimerizing)]-lysine 6-N-methyltransferase)

See also

• Methyllysine
• RuBisCO
• SET domain

Notes and References

1. Magnani R, Nayak NR, Mazarei M, Dirk LM, Houtz RL . Polypeptide substrate specificity of PsLSMT. A set domain protein methyltransferase . The Journal of Biological Chemistry . 282 . 38 . 27857–64 . September 2007 . 17635932 . 10.1074/jbc.m702069200 . free .
2. Mininno M, Brugière S, Pautre V, Gilgen A, Ma S, Ferro M, Tardif M, Alban C, Ravanel S . Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants . The Journal of Biological Chemistry . 287 . 25 . 21034–44 . June 2012 . 22547063 . 3375527 . 10.1074/jbc.m112.359976 . free .