(−)-gamma-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing) explained

(−)-γ-cadinene synthase ((2Z,6E)-farnesyl diphosphate cyclizing)
Ec Number:	4.2.3.62

(−)-γ-Cadinene synthase (EC 4.2.3.62, (2Z,6E)-farnesyl diphosphate cyclizing) ((−)-γ-cadinene cyclase) is an enzyme with the systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase ((−)-γ-cadinene-forming).^[1] This enzyme catalyses the following chemical reaction:

(2Z,6E)-farnesyl diphosphate

\rightleftharpoons (−)-γ-cadinene + [diphosphate]

This enzyme is isolated from the liverwort Heteroscyphus planus.

Notes and References

1. In vitro biosynthesis of cadinanes by cell-free extracts of cultured cells of Heteroscyphus planus . Nabeta K, Fujita M, Komuro K, Katayama K, Takasawa T . J. Chem. Soc., Perkin Trans. 1 . 1997 . 14 . 2065–2070 . 10.1039/a701145h .