(+)-cis-2-Aminomethylcyclopropane carboxylic acid explained

(+)-cis-2-Aminomethylcyclopropane carboxylic acid ((+)-CAMP) is an agonist for the GABAA-rho receptor.[1] [2]

Notes and References

  1. Duke . RK . Chebib . M . Balcar . VJ . Allan . RD . Mewett . KN . Johnston . GA . (+)- and (−)-cis-2-aminomethylcyclopropanecarboxylic acids show opposite pharmacology at recombinant rho(1) and rho(2) GABA(C) receptors . Journal of Neurochemistry . 75 . 6 . 2602–10 . 2000 . 11080214 . 10.1046/j.1471-4159.2000.0752602.x. free .
  2. Carland . JE . Moorhouse . AJ . Barry . PH . Johnston . GA . Chebib . M . Charged residues at the 2' position of human GABAC rho 1 receptors invert ion selectivity and influence open state probability . The Journal of Biological Chemistry . 279 . 52 . 54153–60 . 2004 . 15485818 . 10.1074/jbc.M410625200 . free .

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