(+)-beta-caryophyllene synthase explained

(+)-β-caryophyllene synthase
Ec Number:	4.2.3.89

(+)-β-Caryophyllene synthase (EC 4.2.3.89, GcoA) is an enzyme with systematic name (2Z,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, (+)-β-caryophyllene-forming).^[1] This enzyme catalyses the following chemical reaction:

(2E,6E)-farnesyl diphosphate

\rightleftharpoons (+)-β-caryophyllene + diphosphate

This enzyme also converts the (+)-β-caryophyllene to (+)-caryolan-1-ol.

Notes and References

1. Nakano C, Horinouchi S, Ohnishi Y . Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus . The Journal of Biological Chemistry . 286 . 32 . 27980–7 . August 2011 . 21693706 . 10.1074/jbc.m111.265652 . 3151043. free .