Δ-7-Tetrahydrocannabinol Explained

Δ-7-Tetrahydrocannabinol (Delta-5-THC, Δ⁵-THC; alternatively numbered as Δ-5-Tetrahydrocannabinol, Δ⁷-THC) is a synthetic isomer of tetrahydrocannabinol. The (6aR,9S,10aR)-Δ⁷-THC epimer is only slightly less potent than Δ⁹-THC itself, while the (9R) enantiomer is much less potent.^{[1] [2]}

See also

• 7,8-Dihydrocannabinol
• Delta-3-Tetrahydrocannabinol
• Delta-4-Tetrahydrocannabinol
• Delta-8-Tetrahydrocannabinol
• Delta-10-Tetrahydrocannabinol
• Hexahydrocannabinol

Notes and References

1. Mechoulam R, Ben-Zvi Z, Varconi H, Samuelov Y . Cannabinoid rearrangements: Synthesis of Δ⁵-tetrahydrocannabinol. . Tetrahedron . 1973 . 29 . 11 . 1615–1619 . 10.1016/S0040-4020(01)83406-2 .
2. Huffman JW, Banner WK, Zoorob GK, Joyner HH, Reggio PH, Martin BR, Compton DR . Stereoselective synthesis of the epimeric Δ⁷-tetrahydrocannabinols. . Tetrahedron . 1995 . 51 . 4 . 1017–1032 . 10.1016/0040-4020(94)00995-7 .