| Ștefan Cantacuzino | |
| Succession: | Prince of Wallachia |
| Reign1: | April 1714 – 21 January 1716 |
| Predecessor1: | Constantin Brâncoveanu |
| Successor1: | Nicholas Mavrocordatos |
| House: | Cantacuzino family |
| Father: | Constantin Cantacuzino |
| Birth Date: | ca. 1675 |
| Death Date: | 7 June 1716 |
| Death Place: | Istanbul |
| Religion: | Orthodox |
Ștefan Cantacuzino (Greek, Modern (1453-);: Στέφανος Καντακουζηνός, Stephanos Kantakouzinos), (c. 1675 – 7 June 1716) was a Prince of Wallachia between April 1714 and January 21, 1716, the son of stolnic Constantin Cantacuzino. He was married to Păuna Greceanu-Cantacuzino.
Ștefan was involved in his father's intrigue against Prince Constantin Brâncoveanu, denouncing him to the Ottoman Empire (Wallachia's overlord), and surrendering Brâncoveanu's secret correspondence with the Habsburg monarchy, enemies of the Porte in the Great Turkish War. After obtaining the Prince's deposition, he took the throne in Bucharest as an Ottoman appointee.
His rule coincided with the Habsburg attack led by Prince Eugene of Savoy, during which the Cantacuzinos shook off Ottoman tutelage, informing Stephan Graf Stainville on the Porte's war preparations. A kapucu was sent to depose Prince Ștefan in January 1716, and arrested him together with his father and uncle (the spătar Mihai Cantacuzino). The three of them were executed in Constantinople.
Following Ștefan Cantacuzino's death, the Phanariote rule in Wallachia was established as a way to ensure a tighter Ottoman control over Wallachia.