| Épenouse | |
| Commune Status: | Commune |
| Arrondissement: | Pontarlier |
| Canton: | Valdahon |
| Insee: | 25218 |
| Postal Code: | 25530 |
| Mayor: | Christine Curty[1] |
| Term: | 2023 - 2026 |
| Coordinates: | 47.2153°N 6.4025°W |
| Elevation M: | 650 |
| Elevation Min M: | 546 |
| Elevation Max M: | 672 |
| Area Km2: | 5.75 |
Épenouse (in French pronounced as /ep(ə)nuz/) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.