| Honorific-Prefix: | Çerkes |
| Mehmed Ali | |
| Honorific-Suffix: | Pasha |
| Office1: | Grand Vizier of the Ottoman Empire |
| Term Start1: | 3 April 1624 |
| Term End1: | 28 January 1625 |
| Monarch1: | Murat IV |
| Predecessor1: | Kemankeş Kara Ali Pasha |
| Successor1: | Hafız Ahmed Pasha |
| Birth Date: | 1557 |
| Death Date: | 28 January 1625 (aged 67-68) |
| Death Place: | Tokat (in modern Turkey) |
| Nationality: | Ottoman |
| Blank1: | Origins |
| Data1: | Circassian |
| Alma Mater: | Enderun School |
| Rank: | Silahdar |
Çerkes Mehmed Ali Pasha (; died 28 January 1625) was an Ottoman statesman who served as Grand Vizier of the Ottoman Empire from 1624 to 1625.[1]
Mehmed was of Circassian origins, hence his epithet. He was educated in the Enderun School in Istanbul. At one point, he served as the armorer and bodyguard (Turkish: silahdar) of the sultan. He died of illness on 28 January 1625 in Tokat.